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How Marfan Syndrome Can Impact Your Heart Health


Heart DiseaseAbout 90 percent of people with Marfan syndrome will develop changes in their heart and blood vessels.

If you have Marfan syndrome, you have abnormal connective tissue that can cause your blood vessel walls to weaken and stretch. This damage often affects the aorta, the main artery that carries blood from your heart to the rest of your body.

When the walls of your aorta stretch, you have a higher risk of:

Aortic aneurysm (bulging)
Dissection (tearing)
Rupture (bursting)
These can lead to a life-threatening medical emergency.

In this Q&A, Lars Svensson, MD, PhD, Chairman of Cleveland Clinic’s Sydell and Arnold Miller Family Heart & Vascular Institute, answers five of the most common questions he hears from patients with Marfan syndrome.